Although many people enjoy drinking alcohol, which can be a large part of their social life, it is important to remember that alcohol can have serious adverse effects on people’s health. For all adults, keeping their alcohol intake within drinking guidelines is therefore an important part of maintaining a healthy lifestyle.

For people with LAL-D, it is particularly important to avoid drinking alcohol because of the adverse effects both LAL-D and alcohol have on the liver.[1] Drinking any alcohol will increase the risk of liver damage in addition to LAL-D. [2]

In most people, LAL-D affects the liver in a number of different ways, causing enlargement (hepatomegaly), raised liver enzymes (transaminases), fatty liver disease (steatosis or steatohepatitis), scarring (liver fibrosis and cirrhosis) and liver failure.[2]

To maintain a healthy lifestyle, all adults should only drink alcohol in moderation. However, people with LAL-D must avoid drinking alcohol altogether because of the adverse effects it has on the liver and the risk of increasing the damage to the liver caused by LAL-D.





  1. Ehrmann J, et al. Alcohol-related liver diseases. Cent Eur J Public Health 2019;27(Suppl):S10–4.
  2. Reiner Ž, et al. Lysosomal acid lipase deficiency – an under-recognized cause of dyslipidaemia and liver dysfunction. Atherosclerosis 2014;235:21–30.